Deciphera Pharmaceuticals is a pre-commercial stage biopharmaceutical company focused on improving the lives of cancer patients by addressing key mechanisms of drug resistance that limit the rate and/or durability of response to existing cancer therapies. Our small molecule drug candidates are directed against an important family of enzymes called kinases, known to be directly involved in the growth and spread of many cancers. We use our deep understanding of kinase biology together with a proprietary chemistry library to purposefully design compounds that maintain kinases in a “switched off” or inactivated conformation. These investigational therapies comprise tumor-targeted agents designed to address therapeutic resistance causing mutations and immuno-targeted agents designed to control the activation of immunokinases that suppress critical immune system regulators, such as macrophages. We have used our platform to develop a diverse pipeline of tumor-targeted and immuno-targeted drug candidates designed to improve outcomes for patients with cancer by improving the quality, rate and/or durability of their responses to treatment.
We offer an outstanding culture and opportunity for personal and professional growth based on these key principles:
· providing a collaborative, energized and fun work environment where people are empowered and supported in the achievement of their career goals
· a diverse and multi-disciplinary workforce
· dedicated and talented people who are passionate about achieving excellence in all they do
· a work environment that allows you to balance your priorities
· above all else, a commitment to the patients we serve
We are seeking a Clinical Data Manager who can contribute to data management activities in support of Deciphera studies across all stages of clinical drug development. This position will report to the Associate Director of Data Management and will be located in the Waltham, MA office.
The Clinical Data Manager is responsible for the performance of data management tasks from study start-up, inclusive of database design, through database lock for assigned projects within electronic data capture (EDC) systems. S/he is responsible for assisting with the creation of CRFs, actively involved in User Acceptance Testing (UAT), data cleaning, query generation and management, and assisting in the review of relevant data management documents. The Clinical Data Manager is responsible for overall data quality and documentation.