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Senior Bioinformatics Engineer

South San Francisco, CA - Neuroscience Research & Drug Discovery Full-time
Verge Genomics is seeking a hands-on technical lead to ensure the best bioinformatic practices and processes are applied to our drug discovery platform, while mentoring team members on these concepts. You will apply a variety of next-generation sequencing (NGS) data analysis methods, including RNAseq, to support our drug discovery efforts. If you have a mastery of common bioinformatics concepts, including genome sequencing and gene expression, plus a passion for analysis in Python/R, then we would love to hear from you! 

We're looking for a superstar with growth potential and a willingness to be a technical leader within our team; having strong project management and communication skills will be an asset to become a team captain/”coach”.

We’re inventing something new and different here at Verge Genomics; please apply if you thrive in the face of ambiguity, are unafraid to proactively ask questions, and love solving new problems on the scientific vanguard. 

Company Summary:
Help us revolutionize the way drugs are discovered & developed:
Currently, it takes on average 12 years and $2.6 billion to get a single drug to market, with the drug discovery and development process costing $1.4 billion. Verge Genomics has raised >$36 million to change this broken model by fueling the drug discovery pipeline with machine learning.

Verge Genomics is a next-generation biopharmaceutical start-up using systems biology to accelerate the development of life-saving treatments for neurodegenerative diseases. Our platform uses patient genomes, gene expression, and epigenomics to identify new therapeutic gene targets, predict effective drugs, and stratify patient subpopulations for increased clinical success. Verge's approach offers a breakthrough opportunity to identify drugs that dramatically improve patient outcomes and fundamentally lower the cost curve of pharmaceutical development.

We are looking for extraordinary individuals to join our motivated team in taking on our generation’s biggest healthcare challenges: Alzheimer’s Disease, ALS, and Parkinson’s Disease. Our employees are our most important asset; we are a team of founders, excited to learn, roll up our sleeves, and make a real impact.
What you’ll do:
  • Become a technical lead and engineering expert on our platform for analyses including RNA sequencing, gene coexpression network discovery, identification of master regulator genes, and analysis of drug screening data
  • Improve the usability and rigor of our platform, by incorporating new methods, building automated testing suites, and developing performance benchmarks
  • Collaborate with the team to engineer new analysis methods into our platform
  • Improve the usability of our platform by engineering new features, such as server-side job queues and web portal-based GUIs. 
  • Collaborate with our team to document our methods for long-lasting value, including code “cookbooks” and web-based documentation of our API
  • Ensure the rigor of our software platform, including code reviews and management of our GitHub repositories
  • Coach and mentor team members with technical aspects of bioinformatics projects
  • Architect additional ontologies into our PostgreSQL database, as needed, to support new methods and data
  • What we're looking for:
  • MS/PhD with 4+ years of industry experience
  • Mastery of engineering bioinformatics analysis pipelines in Python and some familiarity with R
  • Experience working with SQL databases
  • Fluency with managing code repositories (i.e. GitHub), including management of feature requests, pull requests, code reviews, and code styles
  • Experience building solutions in Amazon Web Services (AWS)
  • Understand concepts of web application engineering, including Python Django and its underlying technologies: HTML, CSS, and Javascript
  • Strong desire to work in a start-up environment
  • Passion for software craftsmanship, quality, automation, and continuous improvement
  • Excellent communication (written and verbal) and data presentation skills

  • While the team is currently working from home (WFH), our hope is that you will be open to joining us in person in our South San Francisco office/lab space in the future.

    The startup nature of Verge Genomics provides multiple growth opportunities into other areas of the company. As one of the early employees at Verge, your work will have a direct impact on the foundation of a groundbreaking new drug development model. In addition to competitive compensation and benefits, we offer perks like unlimited vacation/sick days, on-site gym access, and a WFH stipend.

    Verge actively seeks a diverse applicant pool in order to build the strongest possible workforce. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.