ngmbio logo

Scientist, Human Genetics

South San Francisco Biology - Biology - Discovery Full Time
NGM Biopharmaceuticals, Inc. is a clinical stage biotech company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases.  Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to build a company where innovation and cutting-edge science has provided the foundation for a robust drug discovery engine that has a track record of generating one new IND candidate per year.  NGM’s current pipeline of clinical stage programs consists of six drug candidates targeting liver, metabolic, ophthalmic and oncologic diseases. The most advanced drug candidate, aldafermin (NGM282), is in Phase 2b clinical studies in non-alcoholic steatohepatitis (NASH) and is wholly-owned by NGM.  NGM’s strategic collaboration with Merck, with a current term running to March 2022 at the earliest, provide us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates. 

We are currently seeking a driven and creative Scientist to join our rapidly growing human genetics team. The ideal candidate will be an eager-to-learn, self-motivated team player driven by their scientific curiosity and enthusiasm for drug discovery. The primary responsibilities will include shepherding the development of new human genetics-guided target discovery projects and leading analysis and interpretation of genotyped biobank and clinical trial data. The new team member will be expected to work within a cross-functional team generating high-quality human genetics data to fuel NGM’s drug discovery engine.
Responsibilities
  • Design and perform research in human genetics-guided target discovery and validation
  • Establish and optimize pipelines for analysis of human genetics data
  • Employ modern data analysis strategies to elucidate new insights from human genetics datasets
  • Apply pharmacogenomics approaches to support NGM’s clinical programs
  • Introduce new ideas and methodology to enhance research productivity
  • Stay abreast of the latest scientific advancements in human genetics
  • Present results to senior management and other research staff
  • Required Skills and Experience
  • PhD degree in Human Genetics or related field
  • Sustained productivity evidenced by high quality publications
  • Must exhibit a strong understanding of methods in population and/or statistical genetics including, at a minimum, GWAS, burden testing and mendelian randomization
  • Expertise in computational tools for large scale genetic analyses (e.g. PLINK) and statistical computing or programming languages (e.g. R, Python).
  • Previous experience in biological fields outside of Human Genetics is preferred
  • Previous experience in some wet lab techniques is preferred
  • No prior industry experience required
  • Additional Requirements
  • Highly motivated by passion and curiosity for science and drug development
  • Independent, innovative, and creative thinker
  • Excellent attitude toward teamwork and collaboration
  • Outstanding written and verbal communication skills
  • Strong organization and time management skills

  • NGM offers a creative, collaborative, highly challenging scientific environment, along with a strong compensation package that includes salary, stock options, 401(k) and a comprehensive benefits package.

    Interested applicants should apply through the NGM Biopharmaceuticals website: https://www.ngmbio.com/open-positions/

    Note to Recruitment Agencies: Please do not forward any agency résumés. NGM Bio is not responsible for any fees related to résumés that are unsolicited.